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Neurohormonal activation induces intracellular iron deficiency and mitochondrial dysfunction in cardiac cells
BACKGROUND: Iron deficiency (ID) is common in patients with heart failure (HF) and is associated with poor outcomes, yet its role in the pathophysiology of HF is not well-defined. We sought to determine the consequences of HF neurohormonal activation in iron homeostasis and mitochondrial function in...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130332/ https://www.ncbi.nlm.nih.gov/pubmed/34001233 http://dx.doi.org/10.1186/s13578-021-00605-5 |