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Cdk5 regulatory subunit-associated protein 1 knockout mice show hearing loss phenotypically similar to age-related hearing loss

Mitochondrial dysfunction is associated with aging and age-related hearing loss (AHL). However, the precise mechanisms underlying the pathophysiology of hearing loss remain unclear. Cdk5 regulatory subunit-associated protein 1 (CDK5RAP1) enables efficient intramitochondrial translation by catalyzing...

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Detalles Bibliográficos
Autores principales: Miwa, Toru, Wei, Fan-yan, Tomizawa, Kazuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130336/
https://www.ncbi.nlm.nih.gov/pubmed/34001214
http://dx.doi.org/10.1186/s13041-021-00791-w