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KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1

BACKGROUND: KDM6A, a histone demethylase, is frequently mutated in bladder cancer (BCa). However, the role and detailed molecular mechanism of KDM6A involved in bladder cancer progression remains unknown. METHODS: Tissue specimens were used to determine the expression levels and prognostic values of...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Cui, Jianfeng, Zhao, Yajing, Liu, Xiaochen, Chen, Lipeng, Xia, Yangyang, Wang, Yong, Chen, Shouzhen, Sun, Shuna, Shi, Benkang, Zou, Yongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130406/
https://www.ncbi.nlm.nih.gov/pubmed/34006303
http://dx.doi.org/10.1186/s12943-021-01369-9