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mTOR controls endoplasmic reticulum–Golgi apparatus trafficking of VSVg in specific cell types
BACKGROUND: Mammalian/mechanistic target of rapamycin (mTOR) complexes are essential for cell proliferation, growth, differentiation, and survival. mTORC1 hyperactivation occurs in the tuberous sclerosis complex (TSC). mTORC1 localizes to the surface of lysosomes, where Rheb activates it. However, m...
Autores principales: | Koscielny, Alicja, Liszewska, Ewa, Machnicka, Katarzyna, Wezyk, Michalina, Kotulska, Katarzyna, Jaworski, Jacek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130434/ https://www.ncbi.nlm.nih.gov/pubmed/34006213 http://dx.doi.org/10.1186/s11658-021-00262-z |
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