Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures

Traumatic brain injury (TBI) causes chronic symptoms and increased risk of neurodegeneration. Axons in white matter tracts, such as the corpus callosum (CC), are critical components of neural circuits and particularly vulnerable to TBI. Treatments are needed to protect axons from traumatic injury an...

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Detalles Bibliográficos
Autores principales: Bradshaw, Donald V., Knutsen, Andrew K., Korotcov, Alexandru, Sullivan, Genevieve M., Radomski, Kryslaine L., Dardzinski, Bernard J., Zi, Xiaomei, McDaniel, Dennis P., Armstrong, Regina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130449/
https://www.ncbi.nlm.nih.gov/pubmed/34001261
http://dx.doi.org/10.1186/s40478-021-01193-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130449/
https://www.ncbi.nlm.nih.gov/pubmed/34001261
http://dx.doi.org/10.1186/s40478-021-01193-8

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