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An mRNA-based vaccine candidate against SARS-CoV-2 elicits stable immuno-response with single dose

D614G genotype of SARS-CoV-2 virus is highly infectious and responsible for almost all infection for 2nd wave. However, there are currently no reports with D614G as vaccine candidate. Here we report the development of an mRNA-LNP vaccine with D614G variant and characterization in animal model. We ha...

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Detalles Bibliográficos
Autores principales: Nag, Kakon, Chandra Baray, Juwel, Rahman Khan, Maksudur, Mahmud, Asif, Islam, Jikrul, Myti, Sanat, Ali, Rostum, Haq Sarker, Enamul, Kumar, Samir, Hossain Chowdhury, Mobarak, Roy, Rony, Islam, Faqrul, Barman, Uttam, Khan, Habiba, Chakraborty, Sourav, Badsha, Alam, Hossain, Manik, Ahammad, Shamim, Rahman Chowdhury, Mashfiqur, Ghosh, Polash, Islam Shimul, Rayhanul, Ahmmed, Ronzu, Hussain Bhuiya, Eleus, Kumar Biswas, Bipul, Mohiuddin, Mohammad, Sultana, Naznin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Globe Biotech Limited. Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130517/
https://www.ncbi.nlm.nih.gov/pubmed/34039497
http://dx.doi.org/10.1016/j.vaccine.2021.05.035