Cargando…

PRICKLE1, a Wnt/PCP signaling component, is overexpressed and associated with inferior prognosis in acute myeloid leukemia

BACKGROUND: Prickle planar cell polarity protein 1 (PRICKLE1), a core component of the non-canonical Wnt/planar cell polarity (PCP) pathway, was recently reported to be upregulated and correlated with poor prognosis in solid cancers. However, the effect of PRICKLE1 on acute myeloid leukemia (AML) re...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Duanfeng, He, Yanjuan, Mo, Qiuyu, Liu, Enyi, Li, Xin, Huang, Lihua, Zhang, Qin, Chen, Fangping, Li, Yan, Shao, Haigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130533/
https://www.ncbi.nlm.nih.gov/pubmed/34001134
http://dx.doi.org/10.1186/s12967-021-02873-8