Cargando…

PRICKLE1, a Wnt/PCP signaling component, is overexpressed and associated with inferior prognosis in acute myeloid leukemia

BACKGROUND: Prickle planar cell polarity protein 1 (PRICKLE1), a core component of the non-canonical Wnt/planar cell polarity (PCP) pathway, was recently reported to be upregulated and correlated with poor prognosis in solid cancers. However, the effect of PRICKLE1 on acute myeloid leukemia (AML) re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Duanfeng, He, Yanjuan, Mo, Qiuyu, Liu, Enyi, Li, Xin, Huang, Lihua, Zhang, Qin, Chen, Fangping, Li, Yan, Shao, Haigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130533/ https://www.ncbi.nlm.nih.gov/pubmed/34001134 http://dx.doi.org/10.1186/s12967-021-02873-8

Ejemplares similares

Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate
por: Chuykin, Ilya, et al.
Publicado: (2018)

The core PCP protein Prickle2 regulates axon number and AIS maturation by binding to AnkG and modulating microtubule bundling
por: Dorrego-Rivas, Ana, et al.
Publicado: (2022)

CTHRC1 overexpression promotes cervical carcinoma progression by activating the Wnt/PCP signaling pathway
por: Zheng, Mei, et al.
Publicado: (2019)

PCP and Wnt pathway components act in parallel during zebrafish mechanosensory hair cell orientation
por: Navajas Acedo, Joaquin, et al.
Publicado: (2019)

Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium
por: Kunimoto, Koshi, et al.
Publicado: (2022)

Effects of maternal diabetes on the Wnt-PCP pathway and embryogenesis
Publicado: (2015)

Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates
por: Mattes, Benjamin, et al.
Publicado: (2018)

Genetic analysis of Wnt/PCP genes in neural tube defects
por: Chen, Zhongzhong, et al.
Publicado: (2018)

Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil
por: Sellers, Katherine J., et al.
Publicado: (2018)

Pyruvate dehydrogenase kinase 4‐mediated metabolic reprogramming is involved in rituximab resistance in diffuse large B‐cell lymphoma by affecting the expression of MS4A1/CD20
por: Jiang, Duanfeng, et al.
Publicado: (2021)

Prickling or Formication after the use of cocaine
por: Juan Juan, C, et al.
Publicado: (2018)

Wnt signaling pathway-related gene PRICKLE1 is a prognostic biomarker for esophageal squamous cell carcinoma
por: He, Jinxian, et al.
Publicado: (2023)

Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis
por: Corkins, Mark E., et al.
Publicado: (2019)

Correction to: Genetic analysis of Wnt/PCP genes in neural tube defects
por: Chen, Zhongzhong, et al.
Publicado: (2021)

A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway
por: Salašová, Alena, et al.
Publicado: (2017)

Prickle isoforms determine handedness of helical morphogenesis
por: Cho, Bomsoo, et al.
Publicado: (2020)

Prickle is phosphorylated by Nemo and targeted for degradation to maintain Prickle/Spiny-legs isoform balance during planar cell polarity establishment
por: Collu, Giovanna M., et al.
Publicado: (2018)

Nephrocystins play a crucial role in renal epithelial morphogenesis via the regulation of Wnt/PCP components Dishevelled and Rho GTPases
por: Saunier, S, et al.
Publicado: (2012)

CAFET Algorithm Reveals Wnt/PCP Signature in Lung Squamous Cell Carcinoma
por: Hu, Yue, et al.
Publicado: (2011)

Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a
por: Liu, Chunqiao, et al.
Publicado: (2014)

Vangl2, a Core Component of the WNT/PCP Pathway, Regulates Adult Hippocampal Neurogenesis and Age-Related Decline in Cognitive Flexibility
por: Koehl, Muriel, et al.
Publicado: (2022)

Rose without prickle: genomic insights linked to moisture adaptation
por: Zhong, Mi-Cai, et al.
Publicado: (2021)

Depletion of VPS35 attenuates metastasis of hepatocellular carcinoma by restraining the Wnt/PCP signaling pathway
por: Liu, Yi, et al.
Publicado: (2020)

Prickle1 regulates differentiation of frontal bone osteoblasts
por: Wan, Yong, et al.
Publicado: (2018)

On Prickle Cells in the Capsule of a Fibrous Polypus of the Uterus
por: Hardie, J. R.
Publicado: (1875)

On Prickle Cells in the Capsule of a Fibrous Polypus of the Uterus
por: Hardie, Joseph R.
Publicado: (1878)

Morphological studies of rose prickles provide new insights
por: Zhou, Ningning, et al.
Publicado: (2021)

The Drosophila Homologue of the Amyloid Precursor Protein Is a Conserved Modulator of Wnt PCP Signaling
por: Soldano, Alessia, et al.
Publicado: (2013)

Non-canonical WNT/PCP signalling in cancer: Fzd6 takes centre stage
por: Corda, G, et al.
Publicado: (2017)

Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca(2+) pathways in human osteoarthritis osteoblasts
por: Martineau, Xavier, et al.
Publicado: (2017)

Origins of the PCP Shortage
por: Hess, Sharon Folkenroth
Publicado: (2022)

m6A genotypes and prognostic signature for assessing the prognosis of patients with acute myeloid leukemia
por: Fu, Caizhu, et al.
Publicado: (2023)

Papain-like cysteine proteinase zone (PCP-zone) and PCP structural catalytic core (PCP-SCC) of enzymes with cysteine proteinase fold
por: Denessiouk, Konstantin, et al.
Publicado: (2020)

Prickle isoform participation in distinct polarization events in the Drosophila eye
por: Cho, Bomsoo, et al.
Publicado: (2022)

AEG-1 activates Wnt/PCP signaling to promote metastasis in tongue squamous cell carcinoma
por: Pan, Yunping, et al.
Publicado: (2015)

The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye
por: López-Escobar, Beatriz, et al.
Publicado: (2015)

The Drosophila neurogenin Tap functionally interacts with the Wnt-PCP pathway to regulate neuronal extension and guidance
por: Yuan, Liqun, et al.
Publicado: (2016)

COL1A1 promotes metastasis in colorectal cancer by regulating the WNT/PCP pathway
por: Zhang, Zheying, et al.
Publicado: (2018)

PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly
por: Mzoughi, Slim, et al.
Publicado: (2020)

Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer
por: Xu, Huanji, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d0a4tp44f4knu435j6rm7cnttg