Estimating colocalization probability from limited summary statistics

BACKGROUND: Colocalization is a statistical method used in genetics to determine whether the same variant is causal for multiple phenotypes, for example, complex traits and gene expression. It provides stronger mechanistic evidence than shared significance, which can be produced through separate cau...

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Detalles Bibliográficos
Autores principales: King, Emily A., Dunbar, Fengjiao, Davis, Justin Wade, Degner, Jacob F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130535/
https://www.ncbi.nlm.nih.gov/pubmed/34000989
http://dx.doi.org/10.1186/s12859-021-04170-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130535/
https://www.ncbi.nlm.nih.gov/pubmed/34000989
http://dx.doi.org/10.1186/s12859-021-04170-z

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