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USP18 Mediates Interferon Resistance of Dengue Virus Infection

Previous studies demonstrated that dengue virus (DENV) infection developed resistance to type-I interferons (IFNα/β). The underlying mechanism remains unclear. USP18 is a negative regulator of IFNα/β signaling, and its expression level is significantly increased following DENV infection in cell line...

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Detalles Bibliográficos
Autores principales: Ye, Haiyan, Duan, Xiaoqiong, Yao, Min, Kang, Lan, Li, Yujia, Li, Shilin, Li, Bin, Chen, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130619/
https://www.ncbi.nlm.nih.gov/pubmed/34017322
http://dx.doi.org/10.3389/fmicb.2021.682380