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Recent advances in synthetic and medicinal chemistry of phosphotyrosine and phosphonate-based phosphotyrosine analogues

Phosphotyrosine-containing compounds attract significant attention due to their potential to modulate signalling pathways by binding to phospho-writers, erasers and readers such as SH2 and PTB domain containing proteins. Phosphotyrosine derivatives provide useful chemical tools to study protein phos...

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Detalles Bibliográficos
Autores principales: Makukhin, Nikolai, Ciulli, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130623/
https://www.ncbi.nlm.nih.gov/pubmed/34041480
http://dx.doi.org/10.1039/d0md00272k