Alleviation of cisplatin‐induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase‐3 activity

AIMS: Cisplatin (CP), as an effective alkylating agent, is widely used in cancer treatment, while hepatotoxicity is one of its side effects. Gliclazide (GLZ), as an oral hypoglycemic drug, has antioxidant and anti‐inflammatory properties. This study was designed to investigate the protective effect...

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Detalles Bibliográficos
Autores principales: Taghizadeh, Fatemeh, Hosseinimehr, Seyed Jalal, Zargari, Mehryar, Karimpour Malekshah, Abbasali, Mirzaei, Mansoureh, Talebpour Amiri, Fereshteh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130655/
https://www.ncbi.nlm.nih.gov/pubmed/34003600
http://dx.doi.org/10.1002/prp2.788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130655/
https://www.ncbi.nlm.nih.gov/pubmed/34003600
http://dx.doi.org/10.1002/prp2.788

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