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The role of sex, age and genetic polymorphisms of CYP enzymes on the pharmacokinetics of anticholinergic drugs

There is evidence that use of drugs with anticholinergic properties increases the risk of cognitive impairment, and increased exposure to these drugs potentiates this risk. Anticholinergic drugs are commonly used even with associated risk of adverse events. Aging, sex, and genetic polymorphisms of c...

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Detalles Bibliográficos
Autores principales: Trenaman, Shanna C., Bowles, Susan K., Andrew, Melissa K., Goralski, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130657/
https://www.ncbi.nlm.nih.gov/pubmed/34003603
http://dx.doi.org/10.1002/prp2.775