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Gaining acceptance in next generation PBK modelling approaches for regulatory assessments – An OECD international effort

Physiologically Based Kinetic (PBK) models are valuable tools to help define safe external levels of chemicals based on internal doses at target organs in experimental animals, humans and organisms used in environmental risk assessment. As the toxicity testing paradigm shifts to alternative testing...

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Detalles Bibliográficos
Autores principales: Paini, Alicia, Tan, Yu-Mei, Sachana, Magdalini, Worth, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130668/
https://www.ncbi.nlm.nih.gov/pubmed/34027244
http://dx.doi.org/10.1016/j.comtox.2021.100163