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Gaining acceptance in next generation PBK modelling approaches for regulatory assessments – An OECD international effort
Physiologically Based Kinetic (PBK) models are valuable tools to help define safe external levels of chemicals based on internal doses at target organs in experimental animals, humans and organisms used in environmental risk assessment. As the toxicity testing paradigm shifts to alternative testing...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130668/ https://www.ncbi.nlm.nih.gov/pubmed/34027244 http://dx.doi.org/10.1016/j.comtox.2021.100163 |