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Small-molecule inhibitors of carboxylesterase Notum
Notum has recently been identified as a negative regulator of Wnt signaling through the removal of an essential palmitoleate group from Wnt proteins. There are emerging reports that Notum plays a role in human disease, with published data suggesting that targeting Notum could represent a new therape...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Newlands Press Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130783/ https://www.ncbi.nlm.nih.gov/pubmed/33882714 http://dx.doi.org/10.4155/fmc-2021-0036 |