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Intratumoural administration and tumour tissue targeting of cancer immunotherapies

Immune-checkpoint inhibitors and chimeric antigen receptor (CAR) T cells are revolutionizing oncology and haematology practice. With these and other immunotherapies, however, systemic biodistribution raises safety issues, potentially requiring the use of suboptimal doses or even precluding their cli...

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Detalles Bibliográficos
Autores principales:	Melero, Ignacio, Castanon, Eduardo, Alvarez, Maite, Champiat, Stephane, Marabelle, Aurelien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130796/ https://www.ncbi.nlm.nih.gov/pubmed/34006998 http://dx.doi.org/10.1038/s41571-021-00507-y

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