Predictive modeling of biological responses in the rat liver using in vitro Tox21 bioactivity: Benefits from high-throughput toxicokinetics

Computational methods are needed to more efficiently leverage data from in vitro cell-based models to predict what occurs within whole body systems after chemical insults. This study set out to test the hypothesis that in vitro high-throughput screening (HTS) data can more effectively predict in viv...

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Detalles Bibliográficos
Autores principales: Ring, Caroline, Sipes, Nisha S., Hsieh, Jui-Hua, Carberry, Celeste, Koval, Lauren E., Klaren, William D., Harris, Mark A., Auerbach, Scott S., Rager, Julia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130852/
https://www.ncbi.nlm.nih.gov/pubmed/34013136
http://dx.doi.org/10.1016/j.comtox.2021.100166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130852/
https://www.ncbi.nlm.nih.gov/pubmed/34013136
http://dx.doi.org/10.1016/j.comtox.2021.100166

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