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Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts
DNA methylation, chromatin accessibility, and gene expression represent different levels information in biological process, but a comprehensive multiomics analysis of the mammalian heart is lacking. Here, we applied nucleosome occupancy and methylome sequencing, which detected DNA methylation and ch...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130971/ https://www.ncbi.nlm.nih.gov/pubmed/34003819 http://dx.doi.org/10.1371/journal.pbio.3001229 |