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Constitutive activation of MEK5 promotes a mesenchymal and migratory cell phenotype in triple negative breast cancer
Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited targeted therapeutic options. A defining feature of TNBC is the propensity to metastasize and acquire resistance to cytotoxic agents. Mitogen activated protein kinase (MAPK) and extracellular regulated kinase...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131078/ https://www.ncbi.nlm.nih.gov/pubmed/34026925 http://dx.doi.org/10.18632/oncoscience.535 |