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Constitutive activation of MEK5 promotes a mesenchymal and migratory cell phenotype in triple negative breast cancer
Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited targeted therapeutic options. A defining feature of TNBC is the propensity to metastasize and acquire resistance to cytotoxic agents. Mitogen activated protein kinase (MAPK) and extracellular regulated kinase...
Autores principales: | Matossian, Margarite D., Hoang, Van T., Burks, Hope E., La, Jacqueline, Elliott, Steven, Brock, Courtney, Rusch, Douglas B., Buechlein, Aaron, Nephew, Kenneth P., Bhatt, Akshita, Cavanaugh, Jane E., Flaherty, Patrick T., Collins-Burow, Bridgette M., Burow, Matthew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131078/ https://www.ncbi.nlm.nih.gov/pubmed/34026925 http://dx.doi.org/10.18632/oncoscience.535 |
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