Integrated sensing of host stresses by inhibition of a cytoplasmic two-component system controls M. tuberculosis acute lung infection

Bacterial pathogens that infect phagocytic cells must deploy mechanisms that sense and neutralize host microbicidal effectors. For Mycobacterium tuberculosis, the causative agent of tuberculosis, these mechanisms allow the bacterium to rapidly adapt from aerosol transmission to initial growth in the...

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Detalles Bibliográficos
Autores principales: Buglino, John A, Sankhe, Gaurav D, Lazar, Nathaniel, Bean, James M, Glickman, Michael S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131098/
https://www.ncbi.nlm.nih.gov/pubmed/34003742
http://dx.doi.org/10.7554/eLife.65351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131098/
https://www.ncbi.nlm.nih.gov/pubmed/34003742
http://dx.doi.org/10.7554/eLife.65351

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