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Integrated sensing of host stresses by inhibition of a cytoplasmic two-component system controls M. tuberculosis acute lung infection
Bacterial pathogens that infect phagocytic cells must deploy mechanisms that sense and neutralize host microbicidal effectors. For Mycobacterium tuberculosis, the causative agent of tuberculosis, these mechanisms allow the bacterium to rapidly adapt from aerosol transmission to initial growth in the...
Autores principales: | Buglino, John A, Sankhe, Gaurav D, Lazar, Nathaniel, Bean, James M, Glickman, Michael S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131098/ https://www.ncbi.nlm.nih.gov/pubmed/34003742 http://dx.doi.org/10.7554/eLife.65351 |
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