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Integrated transcriptomic and neuroimaging brain model decodes biological mechanisms in aging and Alzheimer’s disease

Both healthy aging and Alzheimer’s disease (AD) are characterized by concurrent alterations in several biological factors. However, generative brain models of aging and AD are limited in incorporating the measures of these biological factors at different spatial resolutions. Here, we propose a perso...

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Detalles Bibliográficos
Autores principales: Adewale, Quadri, Khan, Ahmed F, Carbonell, Felix, Iturria-Medina, Yasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131100/
https://www.ncbi.nlm.nih.gov/pubmed/34002691
http://dx.doi.org/10.7554/eLife.62589