The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos

Ras-responsive element-binding protein 1 (Rreb1) is a zinc-finger transcription factor acting downstream of RAS signaling. Rreb1 has been implicated in cancer and Noonan-like RASopathies. However, little is known about its role in mammalian non-disease states. Here, we show that Rreb1 is essential f...

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Detalles Bibliográficos
Autores principales: Morgani, Sophie M, Su, Jie, Nichols, Jennifer, Massagué, Joan, Hadjantonakis, Anna-Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131102/
https://www.ncbi.nlm.nih.gov/pubmed/33929320
http://dx.doi.org/10.7554/eLife.64811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131102/
https://www.ncbi.nlm.nih.gov/pubmed/33929320
http://dx.doi.org/10.7554/eLife.64811

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