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Carboxylesterase 2 proteins are efficient diglyceride and monoglyceride lipases possibly implicated in metabolic disease

Carboxylesterase 2 (CES2/Ces2) proteins exert established roles in (pro)drug metabolism. Recently, human and murine CES2/Ces2c have been discovered as triglyceride (TG) hydrolases implicated in the development of obesity and fatty liver disease. The murine Ces2 family consists of seven homologous ge...

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Detalles Bibliográficos
Autores principales: Chalhoub, Gabriel, Kolleritsch, Stephanie, Maresch, Lisa K., Taschler, Ulrike, Pajed, Laura, Tilp, Anna, Eisner, Helgit, Rosina, Philipp, Kien, Benedikt, Radner, Franz P.W., Schicho, Rudolf, Oberer, Monika, Schoiswohl, Gabriele, Haemmerle, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131317/
https://www.ncbi.nlm.nih.gov/pubmed/33872605
http://dx.doi.org/10.1016/j.jlr.2021.100075