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An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 3

α-synuclein (αSyn) is a protein known to form intracellular aggregates during the manifestation of Parkinson’s disease. Previously, it was shown that αSyn aggregation was strongly suppressed in the midbrain region of mice that did not possess the gene encoding the lipid transport protein fatty acid...

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Detalles Bibliográficos
Autores principales: Fukui, Naoya, Yamamoto, Hanae, Miyabe, Moe, Aoyama, Yuki, Hongo, Kunihiro, Mizobata, Tomohiro, Kawahata, Ichiro, Yabuki, Yasushi, Shinoda, Yasuharu, Fukunaga, Kohji, Kawata, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131325/
https://www.ncbi.nlm.nih.gov/pubmed/33862084
http://dx.doi.org/10.1016/j.jbc.2021.100663