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An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 3
α-synuclein (αSyn) is a protein known to form intracellular aggregates during the manifestation of Parkinson’s disease. Previously, it was shown that αSyn aggregation was strongly suppressed in the midbrain region of mice that did not possess the gene encoding the lipid transport protein fatty acid...
Autores principales: | Fukui, Naoya, Yamamoto, Hanae, Miyabe, Moe, Aoyama, Yuki, Hongo, Kunihiro, Mizobata, Tomohiro, Kawahata, Ichiro, Yabuki, Yasushi, Shinoda, Yasuharu, Fukunaga, Kohji, Kawata, Yasushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131325/ https://www.ncbi.nlm.nih.gov/pubmed/33862084 http://dx.doi.org/10.1016/j.jbc.2021.100663 |
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