AAV-mediated YAP expression in cardiac fibroblasts promotes inflammation and increases fibrosis

Fibrosis is a hallmark of heart disease independent of etiology and is thought to contribute to impaired cardiac dysfunction and development of heart failure. However, the underlying mechanisms that regulate the differentiation of fibroblasts to myofibroblasts and fibrotic responses remain incomplet...

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Detalles Bibliográficos
Autores principales: Francisco, Jamie, Zhang, Yu, Nakada, Yasuki, Jeong, Jae Im, Huang, Chun-Yang, Ivessa, Andreas, Oka, Shinichi, Babu, Gopal J., Del Re, Dominic P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131354/
https://www.ncbi.nlm.nih.gov/pubmed/34006931
http://dx.doi.org/10.1038/s41598-021-89989-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131354/
https://www.ncbi.nlm.nih.gov/pubmed/34006931
http://dx.doi.org/10.1038/s41598-021-89989-5

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