G protein-coupled receptor kinase 5 deletion suppresses synovial inflammation in a murine model of collagen antibody-induced arthritis

G protein-coupled receptor kinase 5 (GRK5) regulates inflammatory responses via the nuclear factor-kappa B (NF-κB) pathway. This study investigated the functional involvement of GRK5 in the pathogenesis of inflammatory arthritis. Immunohistochemically, rheumatoid arthritis (RA) synovium had a signif...

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Detalles Bibliográficos
Autores principales: Toya, Masakazu, Akasaki, Yukio, Sueishi, Takuya, Kurakazu, Ichiro, Kuwahara, Masanari, Uchida, Taisuke, Tsutsui, Tomoaki, Tsushima, Hidetoshi, Yamada, Hisakata, Lotz, Martin K., Nakashima, Yasuharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131379/
https://www.ncbi.nlm.nih.gov/pubmed/34006987
http://dx.doi.org/10.1038/s41598-021-90020-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131379/
https://www.ncbi.nlm.nih.gov/pubmed/34006987
http://dx.doi.org/10.1038/s41598-021-90020-0

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