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Notch3 inhibits cell proliferation and tumorigenesis and predicts better prognosis in breast cancer through transactivating PTEN

Notch receptors (Notch1–4) play critical roles in tumorigenesis and metastasis of malignant tumors, including breast cancer. Although abnormal Notch activation is related to various tumors, the importance of single receptors and their mechanism of activation in distinct breast cancer subtypes are st...

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Detalles Bibliográficos
Autores principales: Zhang, Yong-Qu, Liang, Yuan-Ke, Wu, Yang, Chen, Min, Chen, Wei-Ling, Li, Rong-Hui, Zeng, Yun-Zhu, Huang, Wen-He, Wu, Jun-Dong, Zeng, De, Gao, Wen-Liang, Chen, Chun-Fa, Lin, Hao-Yu, Yang, Rui-Qin, Zhu, Jiang-Wen, Liu, Wan-Ling, Bai, Jing-Wen, Wei, Min, Wei, Xiao-Long, Zhang, Guo-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131382/
https://www.ncbi.nlm.nih.gov/pubmed/34006834
http://dx.doi.org/10.1038/s41419-021-03735-3