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Structure analysis of deleterious nsSNPs in human PALB2 protein for functional inference

Partner and Localizer of BRCA2 or PALB2 is a typical tumor suppressor protein, that responds to DNA double stranded breaks through homologous recombination repair. Heterozygous mutations in PALB2 are known to contribute to the susceptibility of breast and ovarian cancer. However, there is no compreh...

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Detalles Bibliográficos
Autores principales: Nawar, Noshin, Paul, Anik, Mahmood, Hamida Nooreen, Faisal, Md Ismail, Hosen, Md Ismail, Shekhar, Hossain Uddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131579/
https://www.ncbi.nlm.nih.gov/pubmed/34092963
http://dx.doi.org/10.6026/97320630017424