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A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failure

Acute respiratory failure (ARF) requiring mechanical ventilation, a complicating factor in sepsis and other disorders, is associated with high morbidity and mortality. Despite its severity and prevalence, treatment options are limited. In light of accumulating evidence that mitochondrial abnormaliti...

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Detalles Bibliográficos
Autores principales: Langley, Raymond J., Migaud, Marie E., Flores, Lori, Thompson, J. Will, Kean, Elizabeth A., Mostellar, Murphy M., Mowry, Matthew, Luckett, Patrick, Purcell, Lina D., Lovato, James, Gandotra, Sheetal, Benton, Ryan, Files, D. Clark, Harrod, Kevin S., Gillespie, Mark N., Morris, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131588/
https://www.ncbi.nlm.nih.gov/pubmed/34006901
http://dx.doi.org/10.1038/s41598-021-89716-0