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Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy
Immunometabolic intervention has been applied to treat cancer via inhibition of certain enzymes associated with intratumoral metabolism. However, small-molecule inhibitors and genetic modification often suffer from insufficiency and off-target side effects. Proteolysis targeting chimeras (PROTACs) p...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131624/ https://www.ncbi.nlm.nih.gov/pubmed/34006860 http://dx.doi.org/10.1038/s41467-021-23194-w |