Cargando…

Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

Immunometabolic intervention has been applied to treat cancer via inhibition of certain enzymes associated with intratumoral metabolism. However, small-molecule inhibitors and genetic modification often suffer from insufficiency and off-target side effects. Proteolysis targeting chimeras (PROTACs) p...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Chi, Zeng, Ziling, Cui, Dong, He, Shasha, Jiang, Yuyan, Li, Jingchao, Huang, Jiaguo, Pu, Kanyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131624/
https://www.ncbi.nlm.nih.gov/pubmed/34006860
http://dx.doi.org/10.1038/s41467-021-23194-w