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Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents

Reduced knee weight-bearing from prescription or sedentary lifestyles are associated with cartilage degradation; effects on the meniscus are unclear. Rodents exposed to spaceflight or hind limb unloading (HLU) represent unique opportunities to evaluate this question. This study evaluated arthritic c...

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Detalles Bibliográficos
Autores principales: Kwok, Andy T., Mohamed, Nequesha S., Plate, Johannes F., Yammani, Raghunatha R., Rosas, Samuel, Bateman, Ted A., Livingston, Eric, Moore, Joseph E., Kerr, Bethany A., Lee, Jingyun, Furdui, Cristina M., Tan, Li, Bouxsein, Mary L., Ferguson, Virginia L., Stodieck, Louis S., Zawieja, David C., Delp, Michael D., Mao, Xiao W., Willey, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131644/
https://www.ncbi.nlm.nih.gov/pubmed/34006989
http://dx.doi.org/10.1038/s41598-021-90010-2