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Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents
Reduced knee weight-bearing from prescription or sedentary lifestyles are associated with cartilage degradation; effects on the meniscus are unclear. Rodents exposed to spaceflight or hind limb unloading (HLU) represent unique opportunities to evaluate this question. This study evaluated arthritic c...
Autores principales: | Kwok, Andy T., Mohamed, Nequesha S., Plate, Johannes F., Yammani, Raghunatha R., Rosas, Samuel, Bateman, Ted A., Livingston, Eric, Moore, Joseph E., Kerr, Bethany A., Lee, Jingyun, Furdui, Cristina M., Tan, Li, Bouxsein, Mary L., Ferguson, Virginia L., Stodieck, Louis S., Zawieja, David C., Delp, Michael D., Mao, Xiao W., Willey, Jeffrey S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131644/ https://www.ncbi.nlm.nih.gov/pubmed/34006989 http://dx.doi.org/10.1038/s41598-021-90010-2 |
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