Delineating tesamorelin response pathways in HIV-associated NAFLD using a targeted proteomic and transcriptomic approach

NAFLD is a leading comorbidity in HIV with an exaggerated course compared to the general population. Tesamorelin has been demonstrated to reduce liver fat and prevent fibrosis progression in HIV-associated NAFLD. We further showed that tesamorelin downregulated hepatic gene sets involved in inflamma...

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Detalles Bibliográficos
Autores principales: Fourman, Lindsay T., Stanley, Takara L., Billingsley, James M., Sui, Shannan J. Ho, Feldpausch, Meghan N., Boutin, Autumn, Zheng, Isabel, McClure, Colin M., Corey, Kathleen E., Torriani, Martin, Kleiner, David E., Hadigan, Colleen M., Chung, Raymond T., Grinspoon, Steven K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131688/
https://www.ncbi.nlm.nih.gov/pubmed/34006921
http://dx.doi.org/10.1038/s41598-021-89966-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131688/
https://www.ncbi.nlm.nih.gov/pubmed/34006921
http://dx.doi.org/10.1038/s41598-021-89966-y

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