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A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway

Chromogranin A (CgA) is a hydrophilic glycoprotein released by post-ganglionic sympathetic neurons. CgA consists of a single peptide chain containing numerous paired basic residues, which are typical cleavage sites in prohormones to generate bioactive peptides. It is recognized as a diagnostic and p...

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Detalles Bibliográficos
Autores principales: Wei, Ran, Wu, Qiushuang, Ai, Nana, Wang, Lei, Zhou, Mei, Shaw, Chris, Chen, Tianbao, Ye, Richard Dequan, Ge, Wei, Siu, Shirley W.I., Kwok, Hang Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131715/
https://www.ncbi.nlm.nih.gov/pubmed/34093983
http://dx.doi.org/10.1016/j.csbj.2021.05.003