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Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells

Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a metabolic drug commonly used to treat type 2 diabetes, has been associated with l...

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Detalles Bibliográficos
Autores principales: Alhourani, Abdelnour H., Tidwell, Tia R., Bokil, Ansooya A., Røsland, Gro V., Tronstad, Karl Johan, Søreide, Kjetil, Hagland, Hanne R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131751/
https://www.ncbi.nlm.nih.gov/pubmed/34006970
http://dx.doi.org/10.1038/s41598-021-89861-6