The in vitro micronucleus assay using imaging flow cytometry and deep learning

The in vitro micronucleus (MN) assay is a well-established assay for quantification of DNA damage, and is required by regulatory bodies worldwide to screen chemicals for genetic toxicity. The MN assay is performed in two variations: scoring MN in cytokinesis-blocked binucleated cells or directly in...

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Detalles Bibliográficos
Autores principales: Rodrigues, Matthew A., Probst, Christine E., Zayats, Artiom, Davidson, Bryan, Riedel, Michael, Li, Yang, Venkatachalam, Vidya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131758/
https://www.ncbi.nlm.nih.gov/pubmed/34006858
http://dx.doi.org/10.1038/s41540-021-00179-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131758/
https://www.ncbi.nlm.nih.gov/pubmed/34006858
http://dx.doi.org/10.1038/s41540-021-00179-5

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