Cargando…
The in vitro micronucleus assay using imaging flow cytometry and deep learning
The in vitro micronucleus (MN) assay is a well-established assay for quantification of DNA damage, and is required by regulatory bodies worldwide to screen chemicals for genetic toxicity. The MN assay is performed in two variations: scoring MN in cytokinesis-blocked binucleated cells or directly in...
Autores principales: | Rodrigues, Matthew A., Probst, Christine E., Zayats, Artiom, Davidson, Bryan, Riedel, Michael, Li, Yang, Venkatachalam, Vidya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131758/ https://www.ncbi.nlm.nih.gov/pubmed/34006858 http://dx.doi.org/10.1038/s41540-021-00179-5 |
Ejemplares similares
-
Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning
por: Wills, John W., et al.
Publicado: (2021) -
Optimized automated data analysis for the cytokinesis‐block micronucleus assay using imaging flow cytometry for high throughput radiation biodosimetry
por: Rodrigues, M. A., et al.
Publicado: (2016) -
Automation of the in vitro micronucleus assay using the Imagestream(®) imaging flow cytometer
por: Rodrigues, Matthew A.
Publicado: (2018) -
Genotoxicity of TiO(2) nanoparticles assessed by mini-gel comet assay and micronucleus scoring with flow cytometry
por: Di Bucchianico, Sebastiano, et al.
Publicado: (2017) -
Micronucleus Assay: Pitfalls and Challenges
por: Naderi, Noushin Jalayer
Publicado: (2020)