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Selection for CD26(−) and CD49A(+) Cells From Pluripotent Stem Cells-Derived Islet-Like Clusters Improves Therapeutic Activity in Diabetic Mice

BACKGROUND: Cell therapy of diabetes aims at restoring the physiological control of blood glucose by transplantation of functional pancreatic islet cells. A potentially unlimited source of cells for such transplantations would be islet cells derived from an in vitro differentiation of human pluripot...

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Detalles Bibliográficos
Autores principales: Molakandov, Kfir, Berti, Denise A., Beck, Avital, Elhanani, Ofer, Walker, Michael D., Soen, Yoav, Yavriyants, Karina, Zimerman, Michal, Volman, Ella, Toledo, Itzik, Erukhimovich, Anna, Levy, Alon M., Hasson, Arik, Itskovitz-Eldor, Joseph, Chebath, Judith, Revel, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131825/
https://www.ncbi.nlm.nih.gov/pubmed/34025576
http://dx.doi.org/10.3389/fendo.2021.635405