Pharmacological Inhibition and Genetic Knockdown of BCL9 Modulate the Cellular Landscape of Cancer-Associated Fibroblasts in the Tumor-Immune Microenvironment of Colorectal Cancer

Cancer-associated fibroblasts (CAFs) exert a key role in cancer progression and liver metastasis. They are activated in the tumor microenvironment (TME), but their prometastatic mechanisms are not defined. CAFs are abundant in colorectal cancer (CRC). However, it is not clear whether they are raised...

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Detalles Bibliográficos
Autores principales: Yang, Mengxuan, Wei, Zhuang, Feng, Mei, Zhu, Yuanyuan, Chen, Yong, Zhu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131873/
https://www.ncbi.nlm.nih.gov/pubmed/34026600
http://dx.doi.org/10.3389/fonc.2021.603556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131873/
https://www.ncbi.nlm.nih.gov/pubmed/34026600
http://dx.doi.org/10.3389/fonc.2021.603556

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