Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs

Of late, targeted protein degradation (TPD) has surfaced as a novel and innovative chemical tool and therapeutic modality. By co-opting protein degradation pathways, TPD facilitates complete removal of the protein molecules from within or outside the cell. While the pioneering Proteolysis-Targeting...

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Detalles Bibliográficos
Autores principales: Alabi, Shanique B., Crews, Craig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
JBC Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131913/
https://www.ncbi.nlm.nih.gov/pubmed/33839157
http://dx.doi.org/10.1016/j.jbc.2021.100647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131913/
https://www.ncbi.nlm.nih.gov/pubmed/33839157
http://dx.doi.org/10.1016/j.jbc.2021.100647

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