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IonQuant Enables Accurate and Sensitive Label-Free Quantification With FDR-Controlled Match-Between-Runs

Missing values weaken the power of label-free quantitative proteomic experiments to uncover true quantitative differences between biological samples or experimental conditions. Match-between-runs (MBR) has become a common approach to mitigate the missing value problem, where peptides identified by t...

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Detalles Bibliográficos
Autores principales: Yu, Fengchao, Haynes, Sarah E., Nesvizhskii, Alexey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131922/
https://www.ncbi.nlm.nih.gov/pubmed/33813065
http://dx.doi.org/10.1016/j.mcpro.2021.100077