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Transcriptomic and Immunohistochemical Analysis of Progressive Keratoconus Reveal Altered WNT10A in Epithelium and Bowman's Layer

PURPOSE: To identify global gene expression changes in the corneal epithelium of keratoconus (KC) patients compared to non-KC myopic controls. METHODS: RNA-sequencing was performed on corneal epithelium samples of five progressive KC and five myopic control patients. Selected results were validated...

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Detalles Bibliográficos
Autores principales: Foster, James W., Parikh, Rupin N., Wang, Jiangxia, Bower, Kraig S., Matthaei, Mario, Chakravarti, Shukti, Jun, Albert S., Eberhart, Charles G., Soiberman, Uri S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132000/
https://www.ncbi.nlm.nih.gov/pubmed/33988693
http://dx.doi.org/10.1167/iovs.62.6.16