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Dual Inhibition of DKC1 and MEK1/2 Synergistically Restrains the Growth of Colorectal Cancer Cells

Colorectal cancer, one of the most commonly diagnosed cancers worldwide, is often accompanied by uncontrolled proliferation of tumor cells. Dyskerin pseudouridine synthase 1 (DKC1), screened using the genome‐wide RNAi strategy, is a previously unidentified key regulator that promotes colorectal canc...

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Detalles Bibliográficos
Autores principales: Kan, Guangyan, Wang, Ziyang, Sheng, Chunjie, Chen, Gong, Yao, Chen, Mao, Yizhi, Chen, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132060/
https://www.ncbi.nlm.nih.gov/pubmed/34026451
http://dx.doi.org/10.1002/advs.202004344