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Dual Inhibition of DKC1 and MEK1/2 Synergistically Restrains the Growth of Colorectal Cancer Cells
Colorectal cancer, one of the most commonly diagnosed cancers worldwide, is often accompanied by uncontrolled proliferation of tumor cells. Dyskerin pseudouridine synthase 1 (DKC1), screened using the genome‐wide RNAi strategy, is a previously unidentified key regulator that promotes colorectal canc...
Autores principales: | Kan, Guangyan, Wang, Ziyang, Sheng, Chunjie, Chen, Gong, Yao, Chen, Mao, Yizhi, Chen, Shuai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132060/ https://www.ncbi.nlm.nih.gov/pubmed/34026451 http://dx.doi.org/10.1002/advs.202004344 |
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