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The C. elegans pseudogene sspt-16 (F55A3.7) is required to safeguard germ cells against reprogramming

We recently identified FAcilitates Chromatin Transcription (FACT) as a reprogramming barrier of transcription factor (TF) mediated conversion of germ cells into neurons in C. elegans. FACT is a conserved heterodimer consisting of SPT16 and SSRP1 in mammals. Duplication events during evolution in C....

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Detalles Bibliográficos
Autores principales: Ofenbauer, Andreas, Kraus, Clara Maria, Tursun, Baris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132116/
https://www.ncbi.nlm.nih.gov/pubmed/34017942
http://dx.doi.org/10.17912/micropub.biology.000392