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The C. elegans pseudogene sspt-16 (F55A3.7) is required to safeguard germ cells against reprogramming
We recently identified FAcilitates Chromatin Transcription (FACT) as a reprogramming barrier of transcription factor (TF) mediated conversion of germ cells into neurons in C. elegans. FACT is a conserved heterodimer consisting of SPT16 and SSRP1 in mammals. Duplication events during evolution in C....
Autores principales: | Ofenbauer, Andreas, Kraus, Clara Maria, Tursun, Baris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Caltech Library
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132116/ https://www.ncbi.nlm.nih.gov/pubmed/34017942 http://dx.doi.org/10.17912/micropub.biology.000392 |
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