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Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors

Tumor organoids and patient-derived orthotopic xenografts (PDOXs) are some of the most valuable pre-clinical tools in cancer research. In this protocol, we describe efficient derivation of organoids and PDOX models from glioma patient tumors. We provide detailed steps for organoid culture, intracran...

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Detalles Bibliográficos
Autores principales: Oudin, Anaïs, Baus, Virginie, Barthelemy, Vanessa, Fabian, Carina, Klein, Eliane, Dieterle, Monika, Wantz, May, Hau, Ann-Christin, Dording, Claire, Bernard, Amandine, Michelucci, Alessandro, Yabo, Yahaya A., Kanli, Georgia, Keunen, Olivier, Bjerkvig, Rolf, Niclou, Simone P., Golebiewska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132120/
https://www.ncbi.nlm.nih.gov/pubmed/34027491
http://dx.doi.org/10.1016/j.xpro.2021.100534